Publications

Selection of manuscripts relevant for this project.


Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Athero-sclerotic Plaques.

van der Laan SW, Siemelink MA, Haitjema S, Foroughi Asl H, Perisic L, Mokry M, van Setten J, Malik R, Dichgans M, Worrall BB; METASTROKE Collaboration of the International Stroke Genetics Consortium, Samani NJ, Schunkert H, Erdmann J, Hedin U, Paulsson-Berne G, Björkegren JLM, de Borst GJ, Asselbergs FW, den Ruijter FW, de Bakker PIW, Pasterkamp G.

Circ Genom Precis Med. 2018 Sep;11(9):e002115.



A decade of genome-wide association studies for coronary artery disease: The challenges ahead.

Erdmann J, Kessler T, Munoz Venegas L, Schunkert H.

Cardiovasc Res. 2018 Mar 30. doi: 10.1093/cvr/cvy084.



Sex-Specific Relations of Cardiovascular Risk Factors With Left Ventri-cular Diastolic Dysfunc-tion/Heart Failure With Preserved Ejection Fraction Are Under-reported: A Call for Action.

Eikendal ALM, Gohar A, Rutten FH, Bots ML, Appelman Y, Hofstra L, Cramer MJM, Hoes AW, den Ruijter HM.

J Card Fail. 2018 Mar 13. pii: S1071-9164(18)30098-8.



Intra-Cardiac Release of Extracellular Vesicles Shapes Inflammation Following Myocardial Infarction.

Loyer X, Zlatanova I, Devue C, Yin M, Howangyin KY, Klaihmon P, Guerin CL, Kheloufi M, Vilar J, Zannis K, Fleischmann BK, Hwang DW, Park J, Lee H, Menasche P, Silvestre JS, Boulanger CM

Circ Res. 2018 Mar 28. pii: CIRCRESAHA.117.311326. doi: 10.1161/CIRCRESAHA.117.311326.



Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets.

Lempiäinen H, Brænne I, Michoel T, Tragante V, Vilne B, Webb TR, Kyriakou T, Eichner J, Zeng L, Willenborg C, Franzen O, Ruusalepp A, Goel A, van der Laan SW, Biegert C, Hamby S, Talukdar HA, Foroughi Asl H, CVgenes@target consortium, Pasterkamp G, Watkins H, Samani NJ, Wittenberger T, Erdmann J, Schunkert H, Asselbergs FW, Björkegren JLM

Sci Rep. 2018 Feb 21;8(1):3434.



Renin and aldosterone are not associated with vulnerable plaque characteristics in patients with carotid artery disease.

Hillaert MA, den Ruijter HM, Hoefer IE, Lentjes EG, de Borst GJ, de Vries JPM, Doevendans PA, Pasterkamp G, Timmers L

J Vasc Surg. 2018 Mar 13. S0741-5214(17)31690-7



The morphological and molecular mechanisms of epithelial/endothelial-to-mesenchymal tran-sition and its involve-ment in atherosclerosis.

Wesseling M, Sakkers TR, de Jager SCA, Pasterkamp G, Goumans MJ

Vascul Pharmacol. 2018 Feb 20. S1537-1891(18)30006-5



Extracellular vesicles in coronary artery disease.

Boulanger CM, Loyer X, Rautou PE, Amabile N

Nat Rev Cardiol. 2017 May; 14(5):259-272.



Novel methodologies for biomarker discovery in athero-sclerosis – Concensus statement from the ESC.

Hoefer I, Steffens S, Ala-Korpela M, Bäck M, Badimon L, Bochaton-Piallat ML, Boulanger CM, Caligiuri G, Dimmeler S, Egido J, Evans PC,

Guzik T, Kwak BR, Landmesser U, Mayr M, Monaco C, Pasterkamp G, Tuñón J, Weber C

Eur. Heart Journal, 2015, 36:2635-42.



Altered platelet contents in survivors of early ischemic ventri-cular fibrillation: preliminary findings.

Platelets. 2014;25(1):71-4.

De Jong JS, Nieuwland R, Meijers JC, Korporaal SJ, Akkerman JW, Wilde AA, Dekker LR.



Shear stress regulates endothelial micro-particle release.

Vion AC, Ramkhelawon B, Loyer X, Chironi G, Devue C, Loirand G, Tedgui A, Lehoux S, Boulanger CM

Circ Res. 2013 May 10; 112(10):1323-33.